Linking Disease Associations with Regulatory Information in the Human Genome - Companion website
Marc A. Schaub, Alan P. Boyle, Anshul Kundaje, Serafim Batzoglou, Michael Snyder, Stanford University

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rs76351433

Associations

Study: Genome-wide association study of smoking behaviours in patients with COPD. [PMID:21685187]
First author: Siedlinski M
Journal: Thorax
Date: 06/16/2011
Phenotype: Chronic obstructive pulmonary disease
Study population: 3,441 Caucasian ever-smokers with COPD
Association P-value: 2 x 10-07
Odds ratio [95% confidence interval]: 1.45 [NR]
Gene: SOCS5 - MCFD2
Risk allele: A
Minor allele frequency (controls): 0.96

Lead SNP

rs76351433
Position: chr2:47,022,543 (Open in UCSC Genome Browser)
Distance to nearest TSS: 35,262 bp
GENCODE v7 location: Intergenic region
No regulatory annotation found

Linkage disequilibrium region

Linkage disequilibrium threshold:
 - In all HapMap 2 populations: r2≥0.8 r2≥0.9 r2=1.0 
 - In the HapMap 2 CEU population r2≥0.8 r2≥0.9 r2=1.0 

No SNPs found for this LD threshold.




Credits:
This resource uses data from:
 - The NHGRI GWAS catalog (accessed August 10, 2011)
 - The ENCODE project
 - RegulomeDB
 - The HapMap project

Contact: marc.schaub AT cs.stanford.edu
Last modified: 2011-12-15 01:19:12
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